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Diagnosis and Vascular Pathology with Biophilia Tracker

Developed in the mid-1990s, NLS has played a significant role in the diagnosis of vascular pathology. Its primary advantages are distinguishing vascular from nonvascular structures and arteries from veins, and highly accurately detecting signals of vascular permeability disturbances caused by stenosis or occlusion of the vascular lumen due to atherosclerotic plaques or thrombi, which are typically not visible on B-mode screening alone.

In addition, NLS allows for the diagnosis of portal hypertension, its intensity, and the permeability of portosystemic bypasses. NLS is highly sensitive in determining the extent of peripancreatic vascular involvement in pancreatic cancer, which is crucial for selecting surgical treatment. NLS allows for the detection of damaged renal vessels (venous and arterial), which is crucial for the appropriate selection of antihypertensive medications for arterial hypertension.

Some effective antihypertensive medications, namely angiotensin-converting enzyme (ACE) inhibitors such as capecitabine, enalapril, and beritalic acid, have recently gained popularity, but they can have adverse effects in renal artery stenosis. Therefore, physicians should remember to check the tonometry before prescribing such medications. In such cases, NLS is likely the method of choice.

NLS is essential for the differential diagnosis of benign and malignant liver diseases. Its sensitivity is comparable to the potential of conventional or digital angiography and magnified computer-assisted tomography. Furthermore, NLS is less expensive, simpler, and easier to understand. If needed, it can be used directly at the patient's bedside. NLS can be used in ophthalmology to assess ocular hemodynamics before or after surgical intervention, and in obstetrics to detect disturbed blood flow in the umbilical artery to diagnose fetal growth retardation and predict negative perinatal outcomes.

In summary, NLS is one of the most dynamic technologies, and it is expected to yield new discoveries in the coming years. NLS diagnostic devices that utilize NLS, such as the Biophilia Tracker, are expected to see further development.